Geodesic IntelligenceNovaDDE
Agentic intelligence for drug discovery.
NovaDDE is an AI-native platform for scientific reasoning and drug discovery. It connects frontier AI, scientific knowledge, specialized biological models, and computational tools into a unified agentic system built for complex scientific work.
From questions to scientific workflows.
Drug discovery rarely comes down to a single question. It requires reasoning across literature, biological evidence, molecular structures, computational models, and specialized tools.
NovaDDE brings these capabilities together in one environment, allowing scientists to move from a scientific question to analysis, computation, and actionable insight.
Ask complex scientific questions
Reason across biological mechanisms, disease hypotheses, targets, proteins, and therapeutic strategies.
Search and synthesize scientific knowledge
Navigate scientific literature and other sources of biological knowledge, connecting evidence across papers and disciplines.
Analyze proteins and molecular systems
Explore protein sequences, structures, interactions, mutations, and other molecular properties using specialized models and tools.
Orchestrate computational tools
NovaDDE can select and use specialized tools as part of a larger scientific workflow rather than treating each tool as an isolated endpoint.
Build multi-step workflows
Break complex scientific problems into steps, execute the appropriate analyses, interpret intermediate results, and continue reasoning toward an answer.
Intelligence connected to tools.
NovaDDE brings together multiple layers of scientific intelligence:
Frontier AI
General reasoning, planning, synthesis, and scientific problem solving. You choose the provider your conversations run on.
Connect your own OpenAI, Anthropic or OpenRouter account, on a subscription or an API key.
Scientific Knowledge
Access to the literature and domain-specific biological information needed to ground scientific reasoning.
Eleven literature APIs including PMC full text, Europe PMC and Unpaywall, alongside 40+ bioinformatics services and 20+ gene and variant databases. Results carry reproducible provenance.
Specialized Models
Purpose-built AI models for biological and molecular problems, run on our own GPUs.
BoltzGen, ESMFold and Protenix also run in the model catalog.
Scientific Tools
Computational methods and software that turn reasoning into quantitative analysis, as guided pipelines or as agent-driven jobs.
Twenty-four skills ship with NovaDDE, from cheminformatics and glycoengineering through to figure and manuscript preparation, connected over the Model Context Protocol so the tool layer extends without a release.
NovaDDE orchestrates these components dynamically based on the scientific problem at hand.
One question. A complete scientific workflow.
Start with a scientific objective. NovaDDE decomposes the problem, gathers relevant evidence, invokes specialized models and tools, analyzes the results, and builds toward an answer.
The result is not simply a response — it is a traceable scientific workflow.
Built for drug discovery.
NovaDDE is designed around the workflows that scientists encounter throughout therapeutic discovery. Potential applications include:
- Target and disease biology research
- Literature synthesis and hypothesis generation
- Protein sequence and structure analysis
- Protein interaction analysis
- Therapeutic design exploration
- Computational experiment planning
- Scientific data interpretation
- Multi-step research workflows
The reasoning layer of the stack.
NovaDDE is the reasoning and orchestration layer of Geodesic’s integrated AI and experimental platform.
Together, they create a closed learning loop:
NovaDDE connects intelligence across this stack, helping move scientific ideas from reasoning toward real-world experimentation.
From intelligence to medicines.
We are building NovaDDE to make increasingly powerful AI systems useful for the scientists working to understand biology and create new medicines.